Joining Solutions for Life Science Manufacturing

In life science manufacturing, the integrity of every joint is critical. From catheter assemblies to diagnostic cartridges, joining processes must deliver precision, repeatability, and contamination control while supporting validation and regulatory compliance. Automation NTH provides configurable joining solutions that integrate mechanical, thermal, adhesive, and hybrid processes directly into automated assembly systems. 

Our joining platforms are engineered for scalability and consistency, reducing operator dependency and cycle time while ensuring reliable, high-quality bonds across medical and diagnostic applications. 

Mechanical Joining 

Dependable Assembly Without Heat or Chemicals 

Mechanical joining remains a core method in medical and diagnostic device manufacturing, providing robust fastening without introducing heat or chemical exposure that could compromise sensitive components. 

Key Advantages:
• Compatible with metals, plastics, and composites commonly used in life sciences
• Validation-friendly processes with measurable and controllable parameters
• No thermal impact on sensitive biomaterials or electronics 

How NTH Does It:
• Vision-guided screwdriving and bolting with precise torque control
• Riveting stations with integrated force and position monitoring
• Clinch joining modules for sheet metal components in laboratory equipment
• Servo-driven presses supporting press-fit and snap-fit assembly 

Use Cases:
• Fastening housings for diagnostic instruments
• Crimping connectors in catheter and guidewire manufacturing
• Press-fit components in surgical tools and handheld medical devices 

Thermal Joining (Welding & Related Processes) 

Controlled Energy for Permanent, High-Integrity Bonds 

Thermal joining technologies create strong, permanent bonds essential for structural integrity, fluid sealing, and biocompatibility. Automation NTH integrates multiple welding processes with closed-loop monitoring to ensure consistent, validated performance. 

Key Advantages:
• High-strength bonds suitable for load-bearing or sealed assemblies
• Logged process parameters to support traceability and validation
• Enclosed systems designed to minimize contamination risk 

How NTH Does It:
• Resistance and ultrasonic welding with real-time energy monitoring
• Laser welding with automated beam alignment and process control
• Hot plate welding optimized for medical-grade thermoplastics
• Induction and friction welding for rapid solid-state joining 

Use Cases:
• Ultrasonic welding of diagnostic cartridge housings
• Laser welding of implantable devices with tight tolerance requirements
• Hot plate welding of fluid reservoirs and tubing assemblies 

Adhesive Joining 

Material-Safe Bonding for Complex Assemblies 

Adhesive joining enables bonding of dissimilar materials without mechanical stress or excessive heat. In life science applications, adhesives also support hermetic sealing, vibration damping, and optical performance. 

Key Advantages:
• Gentle process suitable for delicate or sensitive substrates
• Clean, controlled bonding for sterile or contamination-sensitive environments
• Scalable for both high-volume disposables and low-volume implantables 

How NTH Does It:
• Precision dispensing using contact or jetting technologies
• UV curing with integrated radiometry for consistent cure performance
• Thermal and dual-cure ovens with validated temperature control
• Inline inspection verifying adhesive presence and accuracy 

Use Cases:
• UV-curable adhesives in diagnostic cartridges and wearable devices
• Epoxy bonding in microfluidic and optical components
• Silicone sealing in implantable device assemblies 

Hybrid Joining 

Combined Processes for Critical Applications 

Hybrid joining combines mechanical or thermal fastening with adhesive bonding to create joints that are both structurally robust and fluid-tight. These approaches are especially valuable in regulated life science environments. 

Key Advantages:
• Improved load distribution and reduced stress concentrations
• Enhanced sealing for fluid-handling assemblies
• Increased validation confidence through complementary processes 

How NTH Does It:
• Rivet-bonding for durable medical equipment housings
• Weld-bonding for sealed diagnostic modules
• Integrated screw-and-sealant stations for leak-resistant assemblies 

Use Cases:
• Fluid-tight joints in diagnostic cartridges
• Fatigue-resistant structures in surgical robotics
• High-reliability enclosures for implantable devices 

Choosing the Right Joining Strategy 

Capability Best For Speed Precision Consumables 
Mechanical Joining Modular, serviceable assemblies High High Minimal 
Thermal Joining Permanent, structural bonds Moderate–High High Energy 
Adhesive Joining Fragile or multi-material parts Very High Very High Adhesives 
Hybrid Joining Leak-proof, critical structures Moderate High Mixed 

Strategic Value 

Automation NTH’s joining capabilities reflect a commitment to precision, compliance, and innovation in life science manufacturing. Whether producing high-volume diagnostics, sterile disposables, or next-generation implantables, we deliver configurable, validated joining solutions that evolve with your product lifecycle. 

Let’s Build the Right Joining Solution 

Need to assemble a diagnostic cartridge with zero leaks? Weld a biocompatible implant enclosure to tight tolerances? Automate fastening in a validated cleanroom environment? Let’s make it happen. Talk to our automation experts today.

The Guide to
Successful Automated Manufacturing

Download our comprehensive guide to learn more about how to create a successful automated manufacturing system for your organization.