A worldwide leader in Next Generation Sequencing needed a turnkey solution for filling, weighing, capping, labeling, and palletizing tubes filled with a chemical reagent. The product line contained more than 900 permutations of tube/cap/label combinations to be manufactured on this automated system.
Product quality was of utmost importance, which required 100% inspection of Critical to Quality Attributes (CQA), and full traceability of process metrics across the entire product line.
Additionally, the customer had ended their relationship with the previous System Integrator, putting Automationnth in a position to rescue the project, and change the customer’s perspective of what properly executed automation could be.
Requirements Analysis
The customer came to Automationnth with an already existing machine built by another System Integrator that they had parted ways with, which contained no software. This posed a challenge, as we had no involvement in the original concept or design of the equipment.
Our first step was to assess the customer’s requirements, evaluate the design of the existing equipment, and identify any gaps that needed to be addressed. Several areas of improvement were identified, and some stations needed to be completely redesigned. In order to get this equipment back on track and into production, a systematic analysis of every station was performed.
The function and design of each section of the equipment were tied to a User Requirement Specification (URS) line item, and gaps were captured and brought to the customer’s attention.
Addressing Gaps
This analysis exposed several risks in the existing equipment. Because of the tight tolerances on target dispense volumes, the Scale Station needed to be re-designed to accommodate the detection of very small amounts of liquid.
There were also lots of environmental factors around the Scale Station that were currently making it difficult to separate ‘signal’ from ‘noise’. The Scale Station was surrounded by a 36” diameter rotating dial, several 6-axis robots, and several Feeder Stations for feeding consumables (tubes and caps) onto the dial. A new scale nest was designed to mitigate excessive vibration from surrounding stations.
The Capping Station was another area that needed re-design. Cap torque is a Critical to Quality (CTQ) metric, and the existing actuator was insufficient. It used an out-of-date communications protocol, was difficult to perform maintenance on, and contained no closed-loop control for the precision required by the customer.
Automationnth performed a cost analysis which proved that the additional cost of a more modern actuator would pay for itself in terms of savings in development time and maintenance. The new actuator contained integrated closed-loop Scale Nest torque feedback, as well as modern safety protocols, and allowed users to define custom parameters directly from the Human Machine Interface (HMI).
Added Value
Being Customer Centric is a core value at Automationnth. Understanding the difficult situation the customer was in, having invested significant time and money to a design, only to part with the original designer, Automationnth sought opportunities for the customer to leverage existing resources and minimize additional expenses.
One area of opportunity was at the Capping Station. As mentioned, capping torque is a CTQ metric, and the customer wanted to guarantee caps were placed properly onto tubes. The original design called for a camera inspection at the Dispense Station that was no longer necessary.
With the customer’s help, Automationnth was able to repurpose the cameras at the dispense station to be used to visually confirm cap alignment at the capping station. This was a challenge because there were hundreds of combinations of tubes and caps that needed to be inspected, each with its own alignment criteria.
Ultimately, the effort paid off. The cameras were able to be integrated into the Capping Station and provided another layer of confirmation to the customer that each tube had a properly seated cap. The only additional hardware cost was for camera brackets.
Enhanced Opportunities
The ability to clearly see what the customer was dissatisfied with from previous automation experiences served as a silver lining. Automationnth was able to use the information of past systems to create highly customized solutions that met customer visions.
To learn more about implementing custom automation solutions: To learn more about implementing custom automation solutions and turnkey automation equipment.
Pipetting System
One area of enhancement was at the Dispensing Station. The customer had another machine with a similar pipetting system with an interface that they felt had deficiencies. The User Interface (UI) was not easily navigated, and was difficult to troubleshoot.
There were no diagnostic tools for when the system would fail, and maintenance was cumbersome. As a solution, Automationnth completely rebuilt the UI which allowed for user-defined, highly customizable dispensing parameters. The parameters were all stored on the HMI and could be exported, edited offline, and re-imported for ultimate flexibility.
All communications to and from the pipetting system were kept in a log for troubleshooting, and the UI contained a real-time display of the active messages that the pipetting system was receiving.
|
Reference Number |
Description |
Details |
|
1 |
Control Pushbuttons |
Press to upload or download Hamilton data. |
|
2 |
Table Menu |
List of displayable Hamilton data. Press to display a different data set. |
|
3 |
Hamilton Select Drop Down Menu |
Use menu to select Hamilton. |
|
4 |
Table Display |
Displays the table selected from the Table Menu |
|
5 |
File Name Field |
Displays a field to enter the file name. |
|
6 |
Export/Import Table Pushbuttons |
Press to export current table or import a new table. |
|
7 |
Batch Processing Window Navigating Button |
Navigates to the Hamilton Table Batch Processing screen. |
Dispense Robot
Liquid Class Offline Editing
Dispense Robot – Tip Type – HMI Screen
Vision System
Another area of improvement was an Inspection Station which inspected and sorted caps of various sizes and shapes. The original camera did not allow the customer to define size, shape, and RGB limits from the HMI. The camera was replaced with a Cognex InSight model which allowed for custom parameterization:
Cap Type Configuration Tab
This allowed the customer to fine tune their inspection, which was necessary for the wide range of parts they were running.
Results
Overall, the customer received a piece of equipment that met all the original requirements and exceeded expectations regarding the high level of parameterization capability. The customer was very impressed with the ability for Automationnth to take an unfamiliar piece of equipment, assess customer needs, implement the necessary changes, and deliver a fully working piece of automation.
Automationnth provides customers with world-class automated manufacturing systems and solutions. Its services include automation consulting, custom automation systems, and automation optimization.
If you have a current system that is not meeting the required throughout and you’re interested in system optimization, contact us.